Although rare in the United States, a selenium deficiency may lead to serious health issues. Selenomethionine: a review of its nutritional significance, metabolism and toxicity. Studies have demonstrated that increased blood levels of selenium are associated with enhanced immune response. Contents [ show] What is Sodium Selenite? Negro R, et al. Dziaman T, et al. Salonen JT, et al. Metabolism of selenite in human lung cancer cells: X-ray absorption and fluorescence studies. Summary Selenium may help keep your heart healthy by keeping oxidative stress in check and reducing your risk of heart disease. Purpose: Sodium selenite (Na 2 SeO 3) has been known to restore the antioxidant capacity of bone marrow mesenchymal stem cells (BMSCs), reduce the production of reactive oxygen species (ROS) in the cells, and promote cell proliferation and inhibit cell apoptosis. 2. Selenium supplements are mostly available as capsules, tablets, and liquid extracts. Sodium fluoride 0.21 mg. Selenium status in the body and cardiovascular disease: a systematic review and meta-analysis [published correction appears in Crit Rev Food Sci Nutr. Dennert G, et al. Thomson CD, Chisholm A, McLachlan SK, Campbell JM. 2023 Healthline Media LLC. Fang MZ, Zhang X, Zarbl H. Methylselenocysteine resets the rhythmic expression of circadian and growth-regulatory genes disrupted by nitrosomethylurea in vivo. Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice. And a beard trimmed to the length of customers preference finishing off with a straight razor to all the edges for a long lasting look. Vernie LN, et al. Sodium Selenate - an overview | ScienceDirect Topics 2016;70(2):162-169. doi:10.1038/ejcn.2015.78, Jenkins DJA, Kitts D, Giovannucci EL, et al. Washington, DC: International Life Sciences Institute; 2006:480-97. How do I know if I have a selenium deficiency? No supplement is intended to treat, cure, or prevent disease. Ann Intern Med 2007; 147:217-223. 2021;26(23):7084. Its name comes from the Greek word Selene which means moon due to its color and appearance. Ganther HE. 2020;52(8):1198-1208. doi:10.1038/s12276-020-0408-y. Fleming J, Ghose A, Harrison PR. Sutter ME, Thomas JD, Brown J, Morgan B. Selenium toxicity: a case of selenosis caused by a nutritional supplement. Broome CS, et al. Cancer Institute, Chinese Academy of Medical Sciences, Beijing 100021 and Qidong Liver Cancer Institute, Jiangsu, PR China. It also contains 100 mcg of Phytogenic Mineral Catalyst. Signs and Symptoms of Sodium Selenite Exposure: Signs and symptoms of acute sodium selenite exposure include the following: garlic odor on breath, drooling, nasal irritation and burning sensation in nostrils, vomiting, hypotension, dizziness, and poor reflexes. Published 2021 Nov 23. doi:10.3390/molecules26237084, Ventura M, Melo M, Carrilho F. Selenium and thyroid disease: from pathophysiology to treatment. But there is also some evidence that selenium may decrease the toxic side effects of cisplatin. However, more research is needed. Zinc chloride 1.36 mg. Sodium Selenite There is a possible interaction between selenium and cisplatin, a type of chemotherapy used to treat cancer. Ferric chloride 6 H 2 O 0.54 mg. Manganese chloride 4 H 2 O 99.0 g. Estimation of antioxidant intakes from diet and supplements in U.S. adults. Here are 7 incredibly common nutrient deficiencies. Dietary supplements typically contain selenomethionine. Rayman, MP: Selenium and human health. Are You One of Them? WebSodium selenite 99%; CAS Number: 10102-18-8; EC Number: 233-267-9; Synonyms: Disodium selenite; Linear Formula: Na2SeO3; find Sigma-Aldrich-214485 MSDS, Rayman MP, et al. Selenium, glutathione and glutathione peroxidases in blood of patients with chronic liver diseases. Selenium in Poultry Nutrition: from Sodium Selenite to Organic Come treat yourself to the old school hot towel, hot lather and a straight razor shave like the old days. Most of this content is concentrated in the eggs yolk. According to one review, selenium supplementation may be especially beneficial for people with autoimmune thyroiditis, which affects the production of thyroid hormones essential to normal metabolism. Selenium Selenium. Association of antioxidants with memory in a multiethnic elderly sample using the Third National Health and Nutrition Examination Survey. Serum selenium levels and all-cause, cancer, and cardiovascular mortality among US adults. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. Reported average whole-body half-lives of Se-met and selenite in humans were 252 and 102 d, respectively, indicating that Se-met is utilized and reutilized extensively (33 , ,34) . Selenoproteins: molecular pathways and physiological roles. WebSodium selenite, sometimes confused as selenite, is a very hazardous substance used primarily in industrial applications. WebA 2003 study published in the "Journal of Animal Physiology and Animal Nutrition" found that kittens need approximately 0.15 mg/kg of selenium in their diets. Arch Intern Med 2008; 168:404-10. Possible causes of selenium deficiency include: A deficiency in selenium may lead to certain illnesses, including: Additionally, selenium deficiency may be associated with male infertility. In this study, intake of 7.2 mg of organic form and 10 mg of sodium selenite was marked as toxic for dogs, but unfortunately, no information on consumed selenium per body weight was available. Selenium is important for the proper functioning Dennert G, et al. Aliment Pharmacol Ther 2008; 28:689-703. Plasma selenium is positively related to performance in neurological tasks assessing coordination and motor speed. Multiple human studies [64,65,66] have demonstrated a decrease in the toxicity of the standard-of-care chemotherapies (e.g., cisplatin, doxorubicin, cyclophosphamide, and busulfan), and noted that the therapeutic benefit was not adversely affected upon supplementing cancer therapy with selenium either in the form of sodium 2017;2017:1297658. doi: 10.1155/2017/1297658, Zhang X, Liu C, Guo J, Song Y. Selenium status and cardiovascular diseases: meta-analysis of prospective observational studies and randomized controlled trials. Selenium in cancer prevention: a review of the evidence and mechanism of action. This indicates that selenium may help lower heart disease risk by reducing inflammation and oxidative stress in your body. It's important to many aspects of your health, including metabolism and the synthesis of hormones. 2019;24(7):1298. doi:10.3390/molecules24071298, Kang D, Lee J, Wu C, et al. Earthborn Weight Control [Best Low Sodium Recipe]! 2020;58:126435. doi:10.1016/j.jtemb.2019.126435, Barchielli G, Capperucci A, Tanini D. The role of selenium in pathologies: an updated review. The UV spectrum of Se-CEPS showed a peak at 230 nm (Fig. Selenium. An observational study including over 6,000 people found that low serum levels of selenium were associated with an increased risk of autoimmune thyroiditis and hypothyroidism (23). Beck MA. Klein EA, et al. Viral infections including HIV (which causes AIDS), and hepatitis. Sodium selenite is mainly used in the manufacturing of colorless glass and is a water-soluble selenium. Br J Nutr 2004; 92(4): 557-73. WHO 2004: Joint FAO/WHO Expert Consultation on Human Vitamin and Mineral Requirements (1998): Bangkok T. Vitamin and mineral requirements in human nutrition: report of a joint FAO/WHO expert consultation, Bangkok, Thailand, 21-30 September 1998. http://whqlibdoc.who.int/publications/2004/9241546123.pdf 2004. Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse. J Clin Endocrinol Metab 2007; 92:1263-8. Webperoxides.1,2 Sodium selenite is included in medium supplements for use in cell culture (Catalog Numbers I1884 and S5666). Sodium selenite administration was associated with increased incidences of renal papillary regeneration in rats. 9th ed. Li W, Zhu Y, Yan X, et al. Selenium is needed for basic human health. Asia Pac J Clin Nutr 2012; 21:320-6. 5 Sodium selenite can inhibit zinc Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. Although selenium is necessary for good health, getting too much can be dangerous. Selenium: Health Benefits, Side Effects, Uses, Dose Dietary supplements: what you need to know. Selenium supplements like sodium selenite are Sodium selenite (200 g.day 1 for 8 weeks) increased the CD8 + T-lymphocyte-mediated tumour cytotoxicity and NK cell activity by 118% and 82%, respectively. Animal-based foods tend to contain more selenium than vegetables, cereals, and fruits. Dietary supplements are not well-regulated in the United States, and these third parties ensure that supplements actually contain what is listed on the label. Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial. Webselenase oral liquid contains the active ingredient, sodium selenite pentahydrate, which is a source of selenium. Regarding human health, selenium is thought to act mostly as an antioxidant that may be useful in preventing conditions like type 2 diabetes, heart disease, and other metabolic disorders. Selenium is an important mineral for dogs and humans, and some associate it with benefits such as high levels of antioxidants, a reduction in the risk of The Health Benefits of Sodium Selenite - health Selenium and sodium combine chemically to form sodium selenite. National Institutes of Health's Office of Dietary Supplements. Host nutritional selenium status as a driving force for influenza virus mutations. However, even if supplements are third-party tested, they are not necessarily safe for all or effective in general. Several studies have shown that patients with Alzheimers disease have lower blood levels of selenium (15, 16). Consuming selenomethionine is like getting your selenium from a natural source such as a brazil nut but sans the other ingredients. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. These benefits include improved immune system strength, which will enable the body to fight off diseases, a reduction in the occurrence of heart disease, and the Oxidative stress is believed to be involved in both the onset and progression of neurological diseases like Parkinsons, multiple sclerosis, and Alzheimers (14). sodium selenite Osteoarthritis Cartilage 2012; 20:605-13. Apparent absorption of Se was significantly less from SeSp (82%) than from sodium selenite (89%) and SeMet (90%), which did not differ . Taken at normal doses, selenium does not usually have side effects. Office of Disease Prevention and Health Promotion. Biol Trace Elem Res 1997; 56:331-41, Dennert G, Horneber M. Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients. 2022;200(9):3945-3956. doi:10.1007/s12011-021-02997-4. ZRT Laboratory Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and check in about potential interactions with other supplements or medications. Am J Clin Nutr. 2003 Sep; 377(1):32-8. Selenium | Liver Doctor Sodium and selenium are essential nutrients, and for this reason, they are supplemented in all Fromm Family dry foods. Its only needed in small amounts but plays a major role in important processes in your body, including your metabolism and thyroid function. Essential nutrients, like selenium, have DRIs. It is a protein that is derived from plants. This service is only for a beard trim and line placement of the beard using a straight razor blade for that detailed sharp look. Organic and inorganic selenium compounds produce different protein patterns in the blood plasma of rats. Healthline Media does not provide medical advice, diagnosis, or treatment. Sodium selenate treatment improves symptoms and seizure susceptibility Li ZS, Shi KJ. Selenium is a mineral you can consume by eating many foods. Gynecol Oncol 2004; 93:320-7. tiny Pet Food Ingredient, Selenium FASEB J 2001;15:1846-1848. In dose-relation experiments, 82(Se)-enriched selenate or selenite was injected intravenously into male Wistar rats of 8 weeks of age (three rats/group) at single doses of 10, 25, 50, 100 and 200 ug/kg body Sodium Selenite Thus, finding ways to prevent this degenerative disease is imperative. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. 314, 387, Feb 1997, Selenium as a chemo preventative agent in human primary hepatocellular carcinoma. Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit. Hair cut of your choice, includes, fades, tapers, classic style or modern cut with a straight razor finish for a long lasting clean look. Helps support a healthy immune system. According to one meta-analysis of various studies, taking selenium supplements does not affect the risk of cardiovascular (heart) disease. Taking selenium supplements or consuming too much selenium in food may lead to side effects. Too much selenium in your system can cause side effects and toxicity. Br J Nutr 2001; 85: S181-S185. U.S. Department of Agriculture, Agricultural Research Service. Selenium is a trace mineral commonly found in the soil of most regions of the world. The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies. Dietary supplements are not regulated the way drugs are in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. 2022;11(2):251. doi:10.3390/antiox11020251, Hu W, Zhao C, Hu H, Yin S. Food sources of selenium and its relationship with chronic diseases. Institute of Medicine, Food and Nutrition Board. $49.88 $ 49. Sodium Selenite Thus, selenium concentrations in crops depend largely on where they are farmed. Studies have also associated deficiency with an increased risk of death and disease progression in people with HIV, while supplements have been shown to lead to fewer hospitalizations and an improvement in symptoms for these patients (26). It should be noted, though, that we do not know for certain if these study results were due to selenium supplementation, adherence to the Mediterranean diet, or a combination of both. Health Benefits. Selenium is a trace element that is essential for vertebrates and involved in a series of vital metabolic functions. Selenium deficiency & viral infection. Keep selenium supplements out of direct sunlight and store them in a cool, dry place. As demonstrated recently by Swedish scientists, considerably on postpatum day 10; (2) Na selenite (30 nmol/g body wt) injected s.c on day 10; (3) Na selenite s.c on day Tumori 2000; 86(2):105-18. Additionally, browse dog food with Sodium Selenite Benefits. Selenomethionine vs Selenium Yeast - Your Health Remedy Bhattacharya A, et al. Bleys J, et al. Sodium Selenite is an inorganic compound that comes in the form of a colorless solid similar to salt and is a source of selenium. The Recommended Daily Allowances (RDAs) for selenium are as follows: An Adequate Intake (AI) (an average nutrient intake for adequate needs) has been established for infants. These include bacteria, viruses, and parasites. Burbano X, et al. Am J Clin Nutr 2008; 88:1567-75. Vidlar A, et al. doi: 10.1002/14651858.CD005195.pub2. The prevention of primary liver cancer by selenium in high risk populations. Van den Brandt PA, et al. Differential Acute Effects of Selenomethionine Br J Nutr 2008; 100:254-68. 2021;8:696024. See the postnatal supplements our dietitian selected as the best of 2023. A growing body of research proves that organic forms of Se, mainly selenomethionine (SeMet), in poultry diets have a range of important advantages over Tonelli M, et al. Health Benefits Of Sodium Selenite Sodium selenite is a white, sand-like substance that can be used to remove green stains from glass, as a reagent, and as a medication. Campa A, et al. Some research shows that selenium may be beneficial for heart health, diabetes, Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. More research is needed. Selenium Our website services, content, and products are for informational purposes only. In: Bowman B, Russell R, eds. Sodium In fact, thyroid tissue contains a higher amount of selenium than any other organ in the human body (21). Safety and efficacy of sodium selenate as feed additive for - EFSA WebSodium Selenite is an essential antioxidant that helps support overall health. These selenoproteins play essential roles in many processes in the human body, including immunity, metabolism, and the synthesis of hormones. This micronutrient can be found in a wide variety of foods, from oysters to mushrooms to Brazil nuts. Allen NE, et al. {{result.title}} - Fromm Family Foods Researchers found that when selenium was part of an antioxidant supplement, the risk for heart disease and all-cause mortality (death fro all sources) was lower than when selenium or antioxidants were taken separately.
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